BioInvent's partner ThromboGenics reports Day 150 topline data from phase l/ll study of THR-317 in patients with Diabetic Macular Edema

Lund, Sweden – 19 July 2018 – BioInvent International AB (OMXS: BINV) partner ThromboGenics NV has today reported Day 150 topline results from a Phase l/ll, single-masked, multicentre study (THR-317-001) evaluating the safety and efficacy of 2 dose levels (4 mg and 8 mg) of THR-317 for the treatment of diabetic macular edema (NCT03071068).

The study met its primary endpoint of safety for both the 4 mg and 8 mg doses. Whilst the focus of the study was safety, efficacy was also observed.

For further information on the study, see ThromboGenic's press release of 19 July 2018 (www.thrombogenics.com).

ThromboGenics carries all costs for the development of THR-317 and BioInvent is entitled to five percent of the project's economic value.

Notes to editors:

About BioInvent
BioInvent International AB (OMXS: BINV) is focused on the discovery and development of novel and first-in-class immuno-regulatory antibodies to treat cancer. The Company’s clinical programmes are BI-1206, currently in a Phase I/II for non-Hodgkin’s lymphoma and chronic lymphatic leukaemia and TB-403, in cooperation with Oncurious, currently in Phase I/II for medulloblastoma. BioInvent has an exciting pre-clinical portfolio based on novel immuno-modulatory antibodies that target regulatory T cells (T-regs) and tumour-associated myeloid cells. The Company has a strategic research collaboration with Pfizer Inc. and BioInvent also works with leading academic institutions including the University of Southampton, Cancer Research UK, and Penn Medicine. BioInvent generates revenues from global partnerships, including Bayer Pharma, Daiichi Sankyo, and Mitsubishi Tanabe Pharma and from its manufacturing facility for the production of antibodies for research through to late- stage clinical trials. More information is available at www.bioinvent.se  

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